Chemical constituents of cyclic peptides from fibrous roots of Pseudostellaria heterophylla / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 122-126, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-927918
ABSTRACT
Four cyclic peptides were isolated from the 75% ethanol extract of the fibrous roots of Pseudostellaria heterophylla by silica gel, Sephadex LH-20 column chromatography, and semi-preparative HPLC. Through mass spectrometry, NMR and other methods, they were identified as pseudostellarin L(1), heterophyllin B(2), pseudostellarin B(3), and pseudostellarin C(4). Among them, compound 1 was a new cyclic peptide, and compounds 2-4 were isolated from the fibrous roots of P. heterophylla for the first time. None of these compounds displayed cytotoxic activities against MCF-7, A549, HCT-116, and SGC-7901 cells.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptides, Cyclic
/
Magnetic Resonance Spectroscopy
/
Chromatography, High Pressure Liquid
/
Plant Roots
/
Caryophyllaceae
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2022
Type:
Article
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