Co-occurrence of an adenoma malignum and an endocervical-type adenocarcinoma of the uterine cervix in a woman with Peutz-Jeghers syndrome / 부인종양
Journal of Gynecologic Oncology
;
: 203-206, 2010.
Article
in English
| WPRIM
| ID: wpr-92959
ABSTRACT
We report a rare co-occurrence of an adenoma malignum and an adenocarcinoma in a 30-year-old woman with Peutz-Jeghers syndrome. The woman was diagnosed with Peutz-Jeghers syndrome based on an endoscopic biopsy after vaginal bleeding. A pelvic examination and an MRI revealed the co-occurrence of a 4x5 cm protruding adenocarcinoma of FIGO stage Ib2 based on a punch biopsy and a 4.5x5.7 cm multilocular cystic mass above the solid cancer. The patient received two courses of neoadjuvant chemotherapy, followed by a laparoscopic radical hysterectomy with pelvic lymph node dissection. Pathologic findings were consistent with adenocarcinoma (40%) and adenoma malignum (60%) confined to the cervix. Three courses of adjuvant chemotherapy were performed and no clinical evidence of recurrence was seen during a 12 month follow-up period. This study will contribute to defining the best diagnosis and treatment for these rare complicating tumors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Uterine Hemorrhage
/
Biopsy
/
Peutz-Jeghers Syndrome
/
Adenocarcinoma
/
Adenoma
/
Cervix Uteri
/
Follow-Up Studies
/
Chemotherapy, Adjuvant
/
Gynecological Examination
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Journal of Gynecologic Oncology
Year:
2010
Type:
Article
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