Gene mutation-negative essential thrombocytosis in children: report of 1 case and review of literature / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 51-54, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-929732
ABSTRACT
Objective:
To investigate the clinical characteristics, diagnosis and treatment methods of children with gene mutation-negative essential thrombocytosis (ET).Methods:
The clinical data of a child with gene mutation-negative ET in the Blood Diseases Hospital of Chinese Academy of Medical Sciences were collected, and the related literature was reviewed.Results:
The epistaxis was the main clinical symptom of this child. He was diagnosed as ET (gene mutation-negative) by bone marrow aspiration and gene detection. After hydroxyurea treatment, the platelet count increased and the clinical symptoms were improved.Conclusions:
The incidence rate of ET in children is low, and the frequency of gene mutation-negative ET in children reported in the literature is different. The large number of samples and long-term follow-up studies are needed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Prognostic study
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2022
Type:
Article
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