The Clinical Usefulness of Tc-99m ECD Brain SPECT in Acute Measles Encephalitis / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 229-234, 2003.
Article
in Korean
| WPRIM
| ID: wpr-93060
ABSTRACT
PURPOSE:
Since the prognosis of measles encephalitis is poor, early diagnosis and proper management are very important to improve clinical outcomes. We compared Tc-99m ECD brain SPECT (SPECT) with MR imaging (MRI) for the detection of acute measles encephalitis. MATERIALS ANDMETHODS:
Eleven patients (M F=4 7, age range 18 months-14 yrs) with acute measles encephalitis were enrolled in this studies. All of them underwent both MRI and SPECT. The results of SPECT were scored from 0 (normal) to 3 (most severe defect) according to perfusion state. We compared two image modalities for the detection of brain abnormality in acute measles encephalitis.RESULTS:
Seven of 11 patients (63.6%) revealed high signal intensity in the white matter on T2WI of MRI, on the other hand all patients (100%) showed hypoperfusion on SPECT. Severe perfusion deficits above score 2 were located with decreasing frequencies in the frontal lobe (81.8%), temporal lobe (72.7%), occipital lobe (27.3%), basal ganglia (27.3%), and parietal lobe (9.1%).CONCLUSION:
We conclude that SPECT is more useful than MRI for the detection of brain involvement in patients with acute measles encephalitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parietal Lobe
/
Perfusion
/
Prognosis
/
Temporal Lobe
/
Basal Ganglia
/
Brain
/
Magnetic Resonance Imaging
/
Tomography, Emission-Computed, Single-Photon
/
Early Diagnosis
/
Encephalitis
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nuclear Medicine
Year:
2003
Type:
Article
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