The diagnostic efficacy and safety of endobronchial ultrasound-guided transbronchial needle aspiration as an initial diagnostic tool
The Korean Journal of Internal Medicine
;
: 660-667, 2013.
Article
in English
| WPRIM
| ID: wpr-93089
ABSTRACT
BACKGROUND/AIMS:
Real-time, convex probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is used for the staging of malignant mediastinal lymph nodes. We evaluated the diagnostic efficacy and safety of EBUS-TBNA when used as an initial diagnostic tool.METHODS:
We retrospectively studied 56 patients who underwent EBUS-TBNA as an initial diagnostic tool between August 2010 and December 2011. Procedure purpose were classified into four categories 1) intrathoracic masses adjacent to the central airway; 2) enlarged lymph nodes for concurrent diagnosis and staging in suspected malignancy; 3) enlarged lymph nodes in suspected malignancy cases with inability to perform percutaneous core needle biopsy (PCNB); and 4) solely mediastinal masses/lymph nodes in lieu of mediastinoscopy.RESULTS:
The diagnostic accuracy of EBUS-TBNA regardless of procedure purpose was calculated to be 83.9%. Furthermore, the diagnostic accuracy of malignant disease was significantly higher than benign disease (93.9% vs. 70.6%, p < 0.001). The diagnostic accuracy of EBUS-TBNA for each disease is as follows tuberculosis, 50%; sarcoidosis, 60%; aspergillosis, 100%; lung abscess, 100%; lung cancer, 93%; and lymphoma, 100%. There were minor complications in seven patients during the EBUS-TBNA procedure. The complications included mild hypoxia and bleeding.CONCLUSIONS:
In conclusion, EBUS-TBNA is a useful initial diagnostic tool for both benign and malignant diseases. EBUS-TBAN is also a very safe procedure and less invasive compared to mediastinoscopy or PCNB.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tomography, X-Ray Computed
/
Predictive Value of Tests
/
Retrospective Studies
/
Risk Factors
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Endoscopic Ultrasound-Guided Fine Needle Aspiration
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Biopsy, Large-Core Needle
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Lung Diseases
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Lung Neoplasms
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Lymph Nodes
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Lymphatic Metastasis
Type of study:
Diagnostic study
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Etiology study
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Observational study
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Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
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Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2013
Type:
Article
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