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The diagnostic efficacy and safety of endobronchial ultrasound-guided transbronchial needle aspiration as an initial diagnostic tool
The Korean Journal of Internal Medicine ; : 660-667, 2013.
Article in English | WPRIM | ID: wpr-93089
ABSTRACT
BACKGROUND/

AIMS:

Real-time, convex probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is used for the staging of malignant mediastinal lymph nodes. We evaluated the diagnostic efficacy and safety of EBUS-TBNA when used as an initial diagnostic tool.

METHODS:

We retrospectively studied 56 patients who underwent EBUS-TBNA as an initial diagnostic tool between August 2010 and December 2011. Procedure purpose were classified into four categories 1) intrathoracic masses adjacent to the central airway; 2) enlarged lymph nodes for concurrent diagnosis and staging in suspected malignancy; 3) enlarged lymph nodes in suspected malignancy cases with inability to perform percutaneous core needle biopsy (PCNB); and 4) solely mediastinal masses/lymph nodes in lieu of mediastinoscopy.

RESULTS:

The diagnostic accuracy of EBUS-TBNA regardless of procedure purpose was calculated to be 83.9%. Furthermore, the diagnostic accuracy of malignant disease was significantly higher than benign disease (93.9% vs. 70.6%, p < 0.001). The diagnostic accuracy of EBUS-TBNA for each disease is as follows tuberculosis, 50%; sarcoidosis, 60%; aspergillosis, 100%; lung abscess, 100%; lung cancer, 93%; and lymphoma, 100%. There were minor complications in seven patients during the EBUS-TBNA procedure. The complications included mild hypoxia and bleeding.

CONCLUSIONS:

In conclusion, EBUS-TBNA is a useful initial diagnostic tool for both benign and malignant diseases. EBUS-TBAN is also a very safe procedure and less invasive compared to mediastinoscopy or PCNB.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Tomography, X-Ray Computed / Predictive Value of Tests / Retrospective Studies / Risk Factors / Endoscopic Ultrasound-Guided Fine Needle Aspiration / Biopsy, Large-Core Needle / Lung Diseases / Lung Neoplasms / Lymph Nodes / Lymphatic Metastasis Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: The Korean Journal of Internal Medicine Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Tomography, X-Ray Computed / Predictive Value of Tests / Retrospective Studies / Risk Factors / Endoscopic Ultrasound-Guided Fine Needle Aspiration / Biopsy, Large-Core Needle / Lung Diseases / Lung Neoplasms / Lymph Nodes / Lymphatic Metastasis Type of study: Diagnostic study / Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: The Korean Journal of Internal Medicine Year: 2013 Type: Article