Research progress on fat aging and the occurrence and development of metabolic syndrome / 中华老年医学杂志

ABSTRACT

Obesity has become a major public health problem that threatens human health.Abdominal obesity, especially the increase in visceral adipose tissue(VAT), can in some cases lead to insulin resistance and other metabolism-related diseases such as diabetes, cardiovascular disease, thrombosis, and pro-inflammatory metabolic abnormalities.Metabolic syndrome is a group of clinical syndromes characterized by the co-occurrence of various metabolic diseases, including insulin resistance and inflammatory response.In a large extent, the occurrence and development of the metabolic syndrome are related to fat aging and visceral obesity related.Visceral obesity is an independent risk factor for cardiovascular events, and can be changed, so by setting realistic goals, by insisting on reasonable exercise and diet control can achieve control of visceral fat, prevention and control of the metabolic syndrome.This review reviews the concept and pathophysiology of metabolic syndrome and the relationship between visceral obesity and metabolic syndrome.