Numbers of positive lymph nodes predict postoperative survival of intrahepatic cholangiocellular carcinoma patients after radical resection / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 901-904, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-933592
ABSTRACT
Objective:
To evaluate prognostic significance of metastated lymph nodes (LN) in patients with intrahepatic cholangio carcinoma (ICC) after radical resection.Methods:
Data were reviewed on 90 patients at Department of Hepatobiliary and Pancreatic Surgery in our hospital from Feb 2013 to Oct 2019, 37 cases had no LN metastasis (N0 group), 21 cases were in N1 group (positive LN<3) and 32 cases in N2 group (positive LN≥3),and Kaplan-Meier method was used to construct survival curve. Univariate and multivariate COX regression analysis was used to screen independent risk factors.Results:
In N0 group the 1-and 3-year survival rates were 57.7% and 35.2%, respectively. In N1 group the 1-and 3-year survival rates were 46.7% and 17.5%, respectively in N2 group. the 1-and 3-year survival rates were 19.6% and 0, respectively. There was statistical significance in overall survival rate among the three groups ( χ2=15.272, P<0.05). Multivariate analysis showed that resection margin ( P=0.009) and the number of positive LN ( P=0.002) were independent risk factors affecting the prognosis of patients.Conclusion:
Resection margin and the number of metastasing LN were closely related to postoperative prognosis of ICC patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of General Surgery
Year:
2021
Type:
Article
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