Pay attention to the research on the mechanism of retinoblastoma and the methods of diagnosis and treatment / 中华眼底病杂志
Chinese Journal of Ocular Fundus Diseases
;
(6): 173-177, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-934289
ABSTRACT
Retinoblastoma (RB) is the most serious eye disease that causes blindness, disability and death in infant. Loss of tumor suppressor gene RB1 leads to tumorigenesis of RB. With continuous innovation and development of new methods, the management of retinoblastoma has experienced a dramatic change from enucleation, external radiotherapy, intravenous chemotherapy, to intra-arterial chemotherapy combined with local treatment, enabling a more favorable outcome for survival, salvage and vision. However, the pathogenesis of RB is unclear in many aspects, the rate of eyeball removal in children with advanced RB remains high, and the innovation of new treatment are needed to be further promoted. Therefore, the key to improve the overall treatment level of RB is to pay attention to the study on pathogenesis, early diagnosis and treatment, as well as strengthen multi-center clinical trials and translational medicine research.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Screening study
Language:
Chinese
Journal:
Chinese Journal of Ocular Fundus Diseases
Year:
2022
Type:
Article
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