Progress of γ-synuclein in tumor proliferation, invasion, migration and drug resistance / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 154-157, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-934647
ABSTRACT
γ-synuclein (SNCG) has been extensively studied for its specific overexpression in various malignant neoplasms. Recently, SNCG has been found to be involved in multiple signaling pathways, including estrogen, AKT-mTOR, mitogen-activated protein kinase (MAPK) and microtubule regulation. SNCG has also been found to be related to the proliferation, invasion, migration and chemotherapy drug resistance of neoplasms. Therefore, SNCG is expected to be the key target of anti-tumor and improving the sensitivity of tumor cells to chemotherapeutic drugs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2022
Type:
Article
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