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The effect of Endocrine disrupting chemicals on myocardial fibrosis and related mechanism / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases ; (12): 156-160, 2022.
Article in Chinese | WPRIM | ID: wpr-935767
ABSTRACT
Endocrine-disrupting chemicals (EDCs) an exogenous agent that interferes with the synthesis, secretion, transport, binding, action, or can mimic the occurrence of natural hormones that damage for the balance of homeostasis. Exposure to EDCs results in damage to human health that may persist in the long term. In recent years, accumulative evidence has demonstrated that EDCs also play a pivotal role in the onset and development of myocardial fibrosis, including heart failure, hypertension and vascular stiffening. Studies indicate that EDCs plays the negative effects of the cardiovascular system, however, EDCs-induced toxicity on heart remains unclear. This review summarized EDCs-induced myocardial fibrosis, and discuss the possible mechanisms of myocardial fibrosis induced by EDCs. This paper could provide further understandings for prevention, diagnosis and treatment of myocardial fibrosis.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Fibrosis / Environmental Exposure / Environmental Pollutants / Endocrine Disruptors Limits: Humans Language: Chinese Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases Year: 2022 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Fibrosis / Environmental Exposure / Environmental Pollutants / Endocrine Disruptors Limits: Humans Language: Chinese Journal: Chinese Journal of Industrial Hygiene and Occupational Diseases Year: 2022 Type: Article