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Research on the antioxidant activity of metabolites from a sponge-derived fungus Alternaria sp. F49 / 药学学报
Yao Xue Xue Bao ; (12): 2120-2125, 2022.
Article in Zh | WPRIM | ID: wpr-936566
Responsible library: WPRO
ABSTRACT
To study the chemical constituents from the the deep-sea fungus Alternaria sp. F49. Seven compounds were isolated from the EtOAc extract by using silica gel, Sephadex LH-20, ODS and HPLC methods. Based on the spectroscopic analysis, their structures were identified as (8R)-5-O-methyl-orcinotriol (1), orcinotriol (2), α-acetylorcinol (3), 3'-hydroxyalternariol 5-O-methyl ether (4), altenusiol (5), altenusin (6), and 5'-methoxy-6-methyl-biphenyl-3,4,3'-triol (7). (8R)-5-O-Methyl-orcinotriol (1) is a new phenolic compound which has never been reported in the literature. Compounds 4-7 showed strong DPPH free radical scavenging activity; whereas compounds 1-7 showed strong ABTS free radical scavenging activity.
Key words
Full text: 1 Index: WPRIM Language: Zh Journal: Yao Xue Xue Bao Year: 2022 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Yao Xue Xue Bao Year: 2022 Type: Article