Prevalence of Y chromosome microdeletions among infertile Mongolian men / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
; : 101-109, 2022.
Article
in En
| WPRIM
| ID: wpr-937326
Responsible library:
WPRO
ABSTRACT
Objective@#Y chromosome microdeletions are the second most common genetic cause of male infertility after Klinefelter syndrome. The aim of this study was to determine the patterns of Y chromosome microdeletions among infertile Mongolian men. @*Methods@#A descriptive study was performed on 75 infertile men from February 2017 to December 2018. Y chromosome microdeletions were identified by polymerase chain reaction. Semen parameters, hormonal levels, and testis biopsy samples were examined. @*Results@#Among 75 infertile men, two cases of Y chromosome microdeletions were identified. The first case had an AZFa complete deletion and the other had an AZFc partial deletion. This study found that the proportion of Y chromosome microdeletions among infertile Mongolian men was 2.66%. @*Conclusion@#The findings can be applied to in vitro fertilization and assisted reproductive technology, and our results will help clinicians improve treatment management for infertile Mongolian couples.
Full text:
1
Index:
WPRIM
Type of study:
Prevalence_studies
/
Prognostic_studies
Language:
En
Journal:
Clinical and Experimental Reproductive Medicine
Year:
2022
Type:
Article