Response to positive patients with COVID-19 self-test visiting the emergency department

ABSTRACT

The real-time polymerase chain reaction (real-time RT-PCR) assay is currently used as a confirmatory test for the detection of coronavirus disease 2019 (COVID-19) since the disease is in community transmission stage in South Korea. However, the Ministry of Food and Drug Safety recently conditionally approved the COVID-19 self-test kit (which is a rapid severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] antigen detection assay), as an additional testing method. The rapid SARS-CoV-2 antigen detection test is difficult to use as a diagnostic tool or screening assay because of the high probability of false-negative results, as it has a lower sensitivity than the RT-PCR assay. However, it can be used as an adjunctive method because of high specificity and faster results. Considering the high specificity of the self-test kit, it is necessary to assume and treat COVID-19 self-test kit positive patients as confirmed COVID-19 patients. Therefore, emergency departments, pre-hospital caregivers and 119 rescuers should prepare a protocol with quarantined spaces and protective equipment for treating COVID-19 self-test kit positive patients, to prevent the spread of infection.