Research progress of the dopaminergic and cholinergic signaling pathways in myopia / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
; (12): 1500-1503, 2022.
Article
in Zh
| WPRIM
| ID: wpr-940011
Responsible library:
WPRO
ABSTRACT
Myopia has become a global public health concern. However, its mechanism remains unclear. Dopamine and acetylcholine, as important neurotransmitters in retina, play a critical role in the formation and inhibition of experimental myopia by binding to specific receptors respectively. Simultaneously, the mechanisms of related signaling pathways during myopia have attracted much attention. Most studies have identified that dopamine and acetylcholine receptor antagonists could inhibit the development of experimental myopiato some extent. Furthermore, pharmacological experiments have suggested that the two signaling pathways cross and influence each other, and there may be common mediators. In this paper, we briefly reviewed the recent researches on dopaminergic and cholinergic signaling pathways and their association during myopia, to provide references for further insights into pathogenesis as well as the prevention and treatment of myopia.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
International Eye Science
Year:
2022
Type:
Article