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Clinical Research on Effectiveness of Mitomycin C on Primary Pterygium With Limbal-Conjunctival Autograft
Journal of the Korean Ophthalmological Society ; : 996-1004, 2009.
Article in Korean | WPRIM | ID: wpr-94269
ABSTRACT

PURPOSE:

To evaluate the effectiveness of Mitomycin C used as a combined therapy along with limbal-conjunctival autograft for primary pterygium.

METHODS:

Thirty eyes of 29 patients received Mitomycin C (0.02% MMC 3 minutes) with limbal-conjunctival autograft, and 30 eyes of 28 patients received limbal-conjunctival autograft alone. Recurrence and complications were evaluated in the patients at 2 weeks, 1, 3, 6 and 12 months postoperatively.

RESULTS:

Mean follow-up periods were 13.4+/-2.1 and 13.9+/-2.9 months, respectively. Between the two groups, recurrence in the conjunctiva or the cornea was not observed during the follow-up period. In the Mitomycin C use group, complications included a granuloma at the donor site (1 eye, 3.3%), wound dehiscence (2 eyes, 6.7%), and subgraft hemorrhage (2 eyes, 6.7%). In comparison, in the group treated with limbal-conjunctival autograft alone, complications included granuloma at the donor site (1 eye, 3.3%), pseudopterygium at the donor site (1 eye, 3.3%), wound dehiscence (3 eyes, 10%), and subgraft hemorrhage (2 eyes, 6.7%).

CONCLUSIONS:

The use of Mitomycin C as an adjuvant therapy has no significant effect on the recurrence rate in primary pterygium with limbal-conjunctival autograft.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Tissue Donors / Pterygium / Follow-Up Studies / Mitomycin / Conjunctiva / Cornea / Eye / Granuloma / Hemorrhage Type of study: Observational study / Prognostic study Limits: Humans Language: Korean Journal: Journal of the Korean Ophthalmological Society Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Tissue Donors / Pterygium / Follow-Up Studies / Mitomycin / Conjunctiva / Cornea / Eye / Granuloma / Hemorrhage Type of study: Observational study / Prognostic study Limits: Humans Language: Korean Journal: Journal of the Korean Ophthalmological Society Year: 2009 Type: Article