Effect of Intravenous Clonidine-Fentanyl on Prevention of Postepidural Shivering / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 707-712, 2001.
Article
in Korean
| WPRIM
| ID: wpr-94424
ABSTRACT
BACKGROUND:
The purpose of this study was to evaluate the efficacy of intravenous clonidine-fentanyl to prevent postepidural shivering in patients undergoing an elective orthopedic surgery.METHODS:
Forty ASA class 1 or 2 patients who received epidural anesthesia for an orthopedic surgery were allocated randomly to two groups. 10 min before epidural anesthesia group 1 received intravenous clonidine 2.0ng/kg and group 2 received clonidine 1.0ng/kg and fentanyl 1.0ng/kg shivering was determined objectively by observing involuntary muscle activity. Mean arterial pressure, heart rate and sedation score were measured at 5 minute intervals during the first 30 minutes following epidural anesthesia.RESULTS:
There were no significant differences between the two groups in the occurrence of shivering, hemodynamic changes and sedation score.CONCLUSIONS:
Intravenous clonidine 2.0ng/kg and the combination of clonidine 1.0ng/kg and fentanyl 1.0ng/kg were not significantly different in occurrence of postepidural shivering. Therefore, a combination of small doses of intravenous clonidine and fentanyl may be safe and useful to reduce postepidural shivering.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Orthopedics
/
Shivering
/
Fentanyl
/
Clonidine
/
Arterial Pressure
/
Heart Rate
/
Hemodynamics
/
Anesthesia, Epidural
/
Muscle, Smooth
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2001
Type:
Article
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