Surface Characteristics and Biocompatibility of Micro Arc Oxidized Titanium Alloy / 대한정형외과연구학회지
Journal of Korean Orthopaedic Research Society
;
: 9-17, 2015.
Article
in Korean
| WPRIM
| ID: wpr-94916
ABSTRACT
PURPOSE:
The aim of this research was to characterize micro arc oxidized titanium (MAO-Ti), accompanied by biocompatibility test in vivo as well as in vitro in comparison to the different types of surface modification; machined, blasted and plasma spray. MATERIALS ANDMETHODS:
XRD and SEM investigations were performed in order to assess the structure and morphology. Biologic and morphologic responses to the osteoblast cell lines (Saos-2) were then examined, using Promeg(R) proliferation assay, alkalinephosphatase activity, alphavbeta3 integrin expression and cytoskeleton staining (Rhodamine-Phallodine). The analysis of gene expression for osteocalcin and collagen I was done through RT-PCR.RESULTS:
MAO-Ti showed more activity on osteointegration and cell differentiation compared to other types of surface modification.CONCLUSION:
In summary, MAO-Ti appears to exhibit more favorable biocompatibility than the compared groups in vitro and in vivo as well.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoblasts
/
Plasma
/
Titanium
/
Cytoskeleton
/
Gene Expression
/
Osteocalcin
/
Cell Differentiation
/
Cell Line
/
Collagen
/
Alloys
Language:
Korean
Journal:
Journal of Korean Orthopaedic Research Society
Year:
2015
Type:
Article
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