Multiple Cutaneous Edema and Infiltration of Signet-ring Cells in the Lymphatics as an Initial Manifestation of Metastatic Gastric Adenocarcinoma / 대한피부과학회지
Korean Journal of Dermatology
;
: 601-604, 2006.
Article
in Korean
| WPRIM
| ID: wpr-94964
ABSTRACT
Signet-ring cells are cells in which the nucleus is crescentically compressed with a cellular border, so that the cell looks like a signet-ring. Many cutaneous signet-ring cell neoplasms originate from the stomach, lung and breast, and these appear to be the most common sites of origin. In skin, the appearance of signet-ring cells within a neoplasm can indicate metastatic adenocarcinoma of the stomach, lung and breast. Thus, the primary origin and other metastatic sites should be evaluated. A 44-year-old man presented with a six month history of cutaneous swelling on the left axillary and left supraclavicular area. Histopathologic findings of the axillary lesion showed signet-ring cells in the lymphatics. These clustered cells were PAS-positive, diastase-resistant, and stained with colloidal iron and CEA. During the work-up study to find the primary origin, we discovered advanced gastric cancer and multiple lymph node metastases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Stomach
/
Stomach Neoplasms
/
Breast
/
Adenocarcinoma
/
Colloids
/
Edema
/
Iron
/
Lung
/
Lymph Nodes
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2006
Type:
Article
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