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Methimazole-Induced Acute Cholestatic Hepatitis in a Patient with History of Simvastatin-Induced Liver Injury
Soonchunhyang Medical Science ; : 163-167, 2014.
Article in Korean | WPRIM | ID: wpr-95063
ABSTRACT
Methimazole and prophylthiouracil are commonly prescribed for patients with hyperthyroidism. The serious side effect of toxic hepatitis caused by these two drugs is well known. According to recent Korean and American management guidelines for hyperthyroidism, mehimazole is recommended as the first-choice antithyroid drug for the treatment of hyperthyroidism. Toxic hepatitis rarely occurs in methimazole users. We report a rare case of a 52-year-old female with toxic hepatitis after methimazole use that had past medical history of simvastatin induced liver injury.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Simvastatin / Drug Interactions / Chemical and Drug Induced Liver Injury / Hepatitis / Hyperthyroidism / Liver / Methimazole Type of study: Practice guideline Limits: Female / Humans Language: Korean Journal: Soonchunhyang Medical Science Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Simvastatin / Drug Interactions / Chemical and Drug Induced Liver Injury / Hepatitis / Hyperthyroidism / Liver / Methimazole Type of study: Practice guideline Limits: Female / Humans Language: Korean Journal: Soonchunhyang Medical Science Year: 2014 Type: Article