Diagnostic Efficacy of the Combination of Urine Cytology, Urinalysis and History in the Follow-up of Bladder Tumor / 대한비뇨기과학회지

ABSTRACT

We studied a retrospective analysis of the diagnostic value of the non-invasive modalities in 6O patients with primary superficial bladder tumors (pTa, pT1) who underwent treated at the Han. yang University Hospital From March 1980 to February 1990. In this study, using empirical cystoscopy follow-up scheme. 17 cystoscopies had to be done to detect each new recurrence. Because of this excessive number of cystosoopies. the diagnostic value of the combination of the following tests were calculated and the sensitivity of the following tests (singly and combined) has been assessed ; (l) urine cytology, (2) red blood cell count in urine sediment and (3) history of symptoms or irritative bladder and hematuria. This study indicated that a combination of non-invasive tests may produce a more rational approach to the follow-up of patients with low stage. low grade transitional cell carcinoma by minimizing the number of cystoscopies. The result indicated that over all recurrence rate was 36.7% (22,60) and 19 cases (86%) were recurred within 2 years and these patients had poor prognosis than patients after 2 years. There were significant increase of recurrence in initial high stage, high grade. high class tumors and the recurrence rate was decreased in patient with instilled adriamycin more than 10 times. The combination of these non-invasive diagnostic tests may constitute a sensitive procedure for the follow-up of bladder tumors. In the case of grade III and muscle-invasive recurrences (>T1), the sensitivity rate was 100%.