Cytotoxic, antioxidant and antimicrobial activities of Nerium oleander collected in Morocco
Asian Pacific Journal of Tropical Medicine
;
(12): 32-37, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-951267
ABSTRACT
Objective:
To investigate the cytotoxic, antioxidant and antibacterial activities of ethanolic and aqueous crude extracts of Nerium oleander (N. oleander) leaves.Methods:
Cytotoxic activities were evaluated by WST-1 bioassay on two human cancer cell lines, namely human colon adenocarcinoma cell line HT-29 and human breast cancer cell line MDA-MB-231. The antioxidant property of N. oleander extracts was assessed by DPPH scavenging and β-carotene bleaching tests. The agar disc diffusion method was used for the determination of antimicrobial activity against different strains.Results:
Using cell viability indices, the WST-1 test revealed that both extracts reduced cell viability in both cell lines. Our results also showed that aqueous extract was more active than ethanolic extract, with IC
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Asian Pacific Journal of Tropical Medicine
Year:
2019
Type:
Article
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