Progress on controversial treatment of mild hypothermia for neonatal hypoxic-ischemic encephalopathy / 国际儿科学杂志

ABSTRACT

Hypoxic-ischemic encephalopathy (HIE) is one of the main causes of neonatal morbidity, mortality and disability.Randomized clinical trials have confirmed the safety and effectiveness of mild hypothermia in the treatment of neonatal HIE, and it can significantly reduce the mortality and disability rate of the disease.Although mild hypothermia can improve the prognosis of some neonates with HIE, there is still some controversy about the selection of treatment subjects, the time window and whether it is effective in the resource-limited countries.This article reviews the research progress on controversial parts of mild hypothermia treatment in recent years, so as to provide the corresponding reference basis for clinical decision-making.