Progress on the application of metabolomics in early diagnosis of neonatal necrotizing enterocolitis / 国际儿科学杂志

ABSTRACT

Neonatal necrotizing enterocolitis(NEC)is a common and dangerous gastrointestinal disease in the neonatal period, with high morbidity and mortality, and the quality of life of some surviving children with NEC is seriously affected.In recent years, the rapid development of metabolomics technology, which provides dynamic qualitative and quantitative analysis of the intermediate and end products involved in biochemical reactions in organisms, explains disease occurrence and development from a systemic perspective, and has broad application prospects in the study of early diagnosis of NEC.The paper reviews the recent research results of metabolomics in the early diagnosis of NEC, aiming to provide a reference basis for the application of metabolomics technology in the early diagnosis of NEC.