Progress of the influence and mechanism of gut-lung axis in premature bronchopulmonary dysplasia / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 620-624, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-954090
ABSTRACT
The gut-lung axis refers to the internal relationship and interaction between the gastrointestinal tract and the respiratory tract at multiple levels.Studies have found that gut microbiota may be closely related to the occurrence and progression of bronchopulmonary dysplasia(BPD)in preterm infants through the gut-lung axis.Studying the mechanism of the interaction between them will help us to extend new therapeutic targets and directions from the perspective of microecology for BPD infants.This article reviews the correlation between gut microbiota and BPD, and the research progress of the mechanism of the gut-lung axis in premature BPD from the aspects of insulin-like growth factor 1, metabolomics, immune regulation, direct transfer, and nutrition.It provides new research ideas for the prevention and treatment of BPD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2022
Type:
Article
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