Microglia: a potential intervention target for vascular cognitive impairment / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 626-630, 2022.
Article
in Chinese
| WPRIM
| ID: wpr-954182
ABSTRACT
Microglia are the main innate immune cells in the central nervous system, which play a variety of roles in the development of the central nervous system and the occurrence of diseases. Recent studies have found that microglia play an important role in the occurrence and development of vascular cognitive impairment (VCI), which can lead to cognitive decline by activating neuroinflammation, oxidative stress, and destroying the blood-brain barrier. This article reviews the role of microglia in the pathophysiology of VCI, aiming to provide a new basis for targeting microglia to treat VCI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2022
Type:
Article
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