High frequency oscillatory ventilation for acute respiratory distress syndrome / 中国小儿急救医学

ABSTRACT

High frequency oscillatory ventilation(HFOV) in the treatment of acute respiratory distress syndrome(ARDS), there are significant differences in clinical research status and evidence level among different participants.HFOV for adult ARDS current clinical evidence suggests that HFOV is not recommended for routine mechanical ventilation in adults with ARDS.HFOV for pediatric ARDS there is no sufficient evidence to show that HFOV is superior to conventional mechanical ventilation.Nor does it prove that HFOV is harmful.The current recommendation is HFOV could be considered as an alternative ventilatory mode in patients with moderate-to-severe pediatric ARDS, whom with conventional mechanical ventilation plateau airway pressures exceed 28 cmH 2O(1 cmH 2O=0.098 kPa) in the absence of clinical evidence of reduced chest wall compliance.HFOV for neonatal ARDS the existing research evidence shows that HFOV can moderately reduce the incidence of chronic lung disease in the premature infants with neonatal ARDS.It has certain advantages in improving oxygenation and alleviating ventilator induced lung injury in acute phase.It also has certain advantages for improving pulmonary function and neurodevelopmental in the long term.