The Effects of Combination of Intrarectal Lidocaine-gel with Periprostatic Lidocaine Injection on the Pain Relief in Repeated Transrectal Prostate Biopsy / 대한비뇨기과학회지
Korean Journal of Urology
;
: 1051-1056, 2005.
Article
in Korean
| WPRIM
| ID: wpr-95577
ABSTRACT
PURPOSE:
We evaluated the effectiveness of intrarectal lidocaine-gel and periprostatic nerve block, or the combined method, on the reduction of pain during repeated transrectal prostate biopsy. MATERIALS ANDMETHODS:
61 patients with a negative pathology after an initial sextant biopsy, with no sedatives or analgesia, were rebiopsied using the 12 extended biopsy technique. The patients scheduled for a repeat prostate biopsy were randomized to the combination method (group 1, 19 patients), periprostatic nerve block (group 2, 23 patients) or intrarectal lidocaine-gel (group 3, 19 patients). After the repeat biopsy, the rectal pain during probe insertion, pain intensity during prostate biopsy and complication rates were recorded. Pain was evaluated by a 10-point linear visual analogue scale (VAS). An ANOVA test was used as the statistical analysis for the assessment of VAS, with p<0.05 considered significant.RESULTS:
No significant difference was found in mean patient age, prostate specific antigen level, prostate volume and complication rates between the groups. The VAS during probe insertion were significantly lower in group 1 and 3 (mean 1.74 and 1.84) than in group 2 (mean 3.96, p<0.001). The VAS during biopsy was significantly lower in group 1 (mean 3.05) than group 3 (mean 4.63, p<0.001).CONCLUSIONS:
Periprostatic nerve block decreased pain during the repeated prostate biopsy, but had no effect on the pain felt during transrectal probe insertion. Intrarectal lidocaine-gel decreased the pain only during probe insertion. However, the combination of intrarectal lidocaine-gel and periprostatic nerve block was effective in reducing the pain, both at biopsy and during probe insertion, in the repeated 12 core biopsy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Prostate
/
Biopsy
/
Prostate-Specific Antigen
/
Analgesia
/
Hypnotics and Sedatives
/
Anesthesia
/
Lidocaine
/
Nerve Block
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Urology
Year:
2005
Type:
Article
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