Correlation analysis of physical indicators with fasting plasma glucose and blood pressure indicators in low-aged and high-aged elderly people in Guangxi / 中华老年医学杂志

ABSTRACT

Objective:To analyze the relationship between physical indicators and blood pressure or fasting plasma glucose levels in the young-old and oldest-old.Methods:Totally 1 516 subjects from the Guangxi Natural Longevity Cohort were screened in this study and physical examination parameters included body mass index(BMI), waist circumference(WC), waist-to-height ratio(WHtR), fasting plasma glucose(FPG)and blood pressure, and the correlations between them were analyzed.Results:The overweight elderly and overweight young elderly groups had an increased risk of concurrent hypertension and impaired fasting glucose, compared with both elderly people with normal BMI and young elderly people with normal BMI( OR=2.66, 95% CI 1.90-3.72; OR=3.03, 95% CI 2.11-4.34). Elderly people with general obesity and young elderly people with general obesity were more likely to have hypertension( OR=5.25, 95% CI 2.07-13.28; OR=4.75, 95% CI 1.84-12.21), impaired fasting glucose( OR=2.95, 95% CI 1.00-8.69; OR=3.06, 95% CI 1.04-9.02), and concurrent hypertension and impaired fasting glucose( OR=7.94, 95% CI 3.04-20.72; OR=8.68, 95% CI 3.28-22.94), whereas underweight young elderly had a reduced risk of hypertension( OR=0.27, 95% CI 0.09-0.80). Elderly people in the central obesity group(WC)showed increased risk of hypertension( OR=1.39, 95% CI 1.04-1.84)and concurrent hypertension and impaired fasting glucose( OR=2.39, 95% CI 1.75-3.27), compared with those in the non-central obesity group.Young elderly people with central obesity had increased risk of hypertension( OR=1.46, 95% CI 1.07-2.00), impaired fasting glucose( OR=1.62, 95% CI 1.14-2.28), and concurrent hypertension and impaired fasting glucose( OR=3.03, 95% CI 2.13-4.32); both elderly people and young elderly people in the central obesity group(WHtR)had increased risk of hypertension( OR=1.35, 95% CI 1.03-1.76; OR=1.55, 95% CI 1.13-2.14), impaired fasting glucose( OR=1.42, 95% CI 1.04-1.94; OR=1.62, 95% CI 1.13-2.31), and concurrent hypertension and impaired fasting glucose( OR=2.20, 95% CI 1.60-3.02; OR=3.22, 95% CI 2.14-4.84). In the elderly group, BMI was correlated with diastolic blood pressure and WHtR was correlated with the fasting blood glucose level. Conclusions:The levels of fasting plasma glucose and blood pressure increase with elevated physical indicator values(BMI, WC, WHtR)in the Guangxi elderly population, and the risk of developing hypertension, impaired fasting glucose, and concurrent hypertension and impaired fasting glucose increases in elderly patients with general obesity and central obesity, with a higher risk in low-aged elderly patients.