Application progress of arterial isolated perfusion chemotherapy in pelvic tumors / 肿瘤研究与临床

ABSTRACT

Pelvic arterial isolated perfusion chemotherapy is a kind of regional chemotherapy. It works by two balloons placed in inferior vena cava and abdominal aorta and tourniquets placed in both lower extremities. Thus pelvic blood circulation can be isolated from the systemic circulation. The chemotherapy drugs are perfused into the pelvic region to achieve local exposure to higher drug concentration than the systematic chemotherapy. The pelvic arterial isolated perfusion chemotherapy is expected to be a new complementary therapy for unresectable pelvic tumors. The use of this technology in neoadjuvant therapy can achieve downgrading of unresectable tumors, and some patients achieve long-term survival after surgery. There are almost no relevant domestic reports yet, and this article discusses the principles, clinical efficacy, safety and complications of this technology.