Does hydatidiform mole predispose to preeclampsia-eclampsia? (a study of 85 cases of hydatidiform mole)

ABSTRACT

Out of 85 cases of hydatidiform mole, 54 or 63.5 had normal blood pressure and normal urinalysisThirty one cases had a blood pressure ranging from 130/80 to 200/100mm. Hg. Two patients had a blood pressure respectively of 174/120 and 180/102 mm. HgThe age of amenorrhea in both the normotensive and hypertensive groups ranged from 2 to 7 monthsThe height of the fundus uteri in the normotensive group ranged from 6 cm. above the symphysis to 2 cm. below the umbilicus except in 9 cases or in 16.7 where it reached the level of umbilicusThe height of the fundus in all of the 31 cases in the hypertensive group was at or above the level of the umbilicusTen of the 31 cases of hypertension had also albuminuria, cylindruria and red blood cells in the urine. Three of these cases had also edema of the lower extremitiesTwo of the cases that showed edema, albuminuria and cylindruria died. They had no convulsions but their autopsy showed the liver lesions of eclampsia. One of them also showed cerebellar hemorrhageThere was no correlation between the age of amenorrhea and hypertension. There was correlation, however, between the hypertension and the height of the fundus uteri. (Summary)