Intra-nasal mass presenting with Cushing's syndrome and CSF rhinorrhea: A case report
Philippine Journal of Surgical Specialties
;
: 20-24, 2017.
Article
in English
| WPRIM
| ID: wpr-959824
ABSTRACT
@#<p style="text-align justify;">This is a case of a 47 year-old female presenting with typical Cushingoid appearance and CSF rhinorrhea. MRI revealed a 4.4 cm x 2.9 cm x 4.5 cm enhancing intranasal mass with evidence of erosion of the left cribriform extending to the left anterior cranial fossa. Dexamethasone suppression test yielded elevated cortisol level. Endoscopic nasal biopsy done showed a round cell tumor positive for ACTH, synaptophysin, chromogranin A, and S-100. Patient subsequently underwent endoscopic endonasal excision of left intranasal mass with creation of pericranial flap for repair of CSF leak. This report is presented to discuss a rare case of ACTH secreting esthesioneurblastoma including its diagnostic challenges and surgical options for repair of anterior cranial fossa defect to address CSF leak particularly by means of a vascularized pericranial flap.</p>
Search on Google
Index:
WPRIM (Western Pacific)
Main subject:
Surgical Flaps
/
Dexamethasone
/
Hydrocortisone
/
Nose
/
Cerebrospinal Fluid Rhinorrhea
/
Synaptophysin
/
Adrenocorticotropic Hormone
/
Cranial Fossa, Anterior
/
Endoscopy
/
Chromogranin A
Limits:
Female
/
Humans
Language:
English
Journal:
Philippine Journal of Surgical Specialties
Year:
2017
Type:
Article
Similar
MEDLINE
...
LILACS
LIS