Comparison of Three Third-generation Anti-HCV Enzyme Immunoassay Tests / 영남의대학술지
Yeungnam University Journal of Medicine
;
: 143-150, 1998.
Article
in Korean
| WPRIM
| ID: wpr-96003
ABSTRACT
The aim of this study was to evaluate domestic enzyme immunoassay(EIA) kit ?LG HCD 3.0?(LG) for the detection of antibody to hepatitis C virus(anti-HCV) in comparision with Axsym HCV version 3.0(Axsym), Cobas Core anti-HCV EIA(Cobas). Cobas kit shows better clear distinction between positive and negative by signal/cutoff ratio(S/C), but it also reveal relatively high false positive rate. The concordance rate of test results between LG and Axsym was 96.2%, between LG and Cobas was 95.5%, and total agreement between three EIA kit was 93.9%. LG were relative poor distinction between positive and negative results, but it could be applied clinically as a screening tool for hepatitis C in general population. The S/C of one false negative result by LG was 0.91, and false positive were less than 4.0, therefore we concluded it is necessary to confirm by immunoblotting assay when S/C were between 0.8 and 4.0.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Immunoblotting
/
Mass Screening
/
Immunoenzyme Techniques
/
Hepatitis C
/
Hepacivirus
Type of study:
Screening study
Language:
Korean
Journal:
Yeungnam University Journal of Medicine
Year:
1998
Type:
Article
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