The effect of timing of oocyte denudation from oocyte retrieval in the total fertilization failure among in vitro fertilization - Intracytoplasmic sperm injection cycles
Philippine Journal of Reproductive Endocrinology and Infertility
;
: 13-22, 2022.
Article
in English
| WPRIM
| ID: wpr-960193
ABSTRACT
@#<p>Objective:
This study aimed to evaluate the effect of oocyte incubation after retrieval in TFF among IVF-ICSI and identify factors affecting total fertilization failure (TFF).</p><p>Methods:
This is a retrospective cohort study, involving 995 IVF cycles using the antagonist protocol that were clustered into three timings of oocyte denudation from retrieval Group 1 <1 hour, Group 2 ?1 hour to <2hours and Group 3 ?2hours. Other variables considered were etiology of infertility, female age, days of stimulation and total number of oocytes retrieved.</p><p>Results:
Overall TFF was 4.5%. TFF among groups were 4.8%, 5.8% and 3.2%, respectively. Multiple logistic regression analysis showed that oocyte incubation prior to denudation for ? 2 hours tend to decrease TFF incidence. Among factors studied, male factor infertility and a low number of oocytes adversely affect TFF.</p><p>Conclusion:
Timing of incubation of oocyte did not significantly affect the occurrence of TFF. Among factors studied, male factor infertility and a low number of oocytes adversely affect TFF.</p>
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Philippine Journal of Reproductive Endocrinology and Infertility
Year:
2022
Type:
Article
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