A comparison of Levobupivacaine and Bupivacaine in caudal anesthesia in children undergoing sub-umbilical operations
The Philippine Children&rsquo
;
s Medical Center Journal;(2): 54-63, 2018.
Article
in English
| WPRIM
| ID: wpr-960209
ABSTRACT
@#<p style="text-align justify;"><strong>BACKGROUND:
</strong> Caudal epidural anesthesia is commonly performed in conjunction with general anesthesia. Bupivacaine and Levobupivacaine are used in epidural blockade that provide anesthesia and analgesia intraoperative and post-operatively.</p><p style="text-align justify;"><strong>OBJECTIVES:
</strong> To compare the intraoperative and postoperative efficacy and safety of Bupivacaine and Levobupivacaine in children undergoing elective sub-umbilical operations under general and caudal anesthesia.</p><p style="text-align justify;"><strong>METHODS:
</strong> Randomized control trial done in Philippine Children's Medical Center. Sixty-one subjects aged 6-months -8 years old, ASA I-II, undergoing subumbilical operations were randomly grouped to receive Bupivacaine and Levobupivacaine during anesthesia induction. Hemodynamic parameters, Bromage, and CHIPPS were recorded.</p><p style="text-align justify;"><strong>RESULTS:
</strong> Results suggest both drugs have a significant effect in lowering heart rate and MAP. Bromage scores for patients from both groups are consistent at 0. The number of patients with a CHIPPS classification of 4-10, is significantly higher for bupivacaine group than levobupivacaine group.</p><p style="text-align justify;"><strong>CONCLUSION:
</strong> Both Bupivacaine and Levobupivacaine provide adequate analgesia intraoperatively with no reports of intraoperative movement, increased inhalational agent concentration and additional intravenous analgesics. Post-operatively, no adverse effects and motor block was noted however Levobupivacaine has a longer efficacy as it required lesser rescue does post-operatively compared to Bupivacaine. </p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bupivacaine
/
Monitoring, Intraoperative
/
Levobupivacaine
/
Anesthesia, Caudal
Limits:
Humans
Language:
English
Journal:
The Philippine Children’s Medical Center Journal
Year:
2018
Type:
Article
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