Hypereosinophilic Syndrome with Hepatic Involvement: US, CT and MRI Findings

ABSTRACT

PURPOSE: To evaluate the findings of US, CT and MRI in the hepatic involvement of hypereosinophilic syndrome. MATERIALS AND METHODS: We reviewed imaging findings of hypereosinophilic syndrome with hepatic involvement innine patients. Imaging studies were US(n=9), conventional CT(CCT, n=6), dynamic incremental CT(DICT, n=3), and MRIwith conventional spin-echo sequence(MRI-CSE, n=3). For DICT, we obtained images of the early arterial phase(n=1),portal venous phase(n=3) and the late venous phase(n=3). T1WI were obtained with 600-700 msec/13-17 msec(TR/TE) and T2WI were obtained with 1850-2300 msec/80-90 msec(n=3). Gadolinium enhanced T1WI were also obtained(n=2). RESULTS: US showed multiple hypoechoic or isoechoic nodules(7/9) and appeared normal(2/9). CCT showed multiplehypodense nodules(5/6) and appeared normal(1/6). DICT showed patchy, multiple hypodense nodules and showed hepaticnodules during the portal venous phase only(3/3). MRI-CSE showed one to several focal high-signal nodules on T2WIand subtle low-signal nodules on T1WI(2/3), and showed several subtle high-signal lesions on Gd-enhanced T1WI(1/2)and appeared normal on T1, T2WI(1/3). CONCLUSION: Hepatic involvement of hypereosinophilic syndrome showed varied imaging findings on US, CT and MRI.