Retinoblastoma vaccine

ABSTRACT

We have prepared a retinoblastoma autolyzed cell vaccine which seems to be the first of its kind. It can be used safely in rabbits and children with retinoblastoma. Its potency is enhanced by adjuvants. Its immunizing potency is demonstrated in rabbits. The direct FA technique pointed to the presence of specific antigen on the surface of the retinoblastoma cell. Its effectivity as an additional therapy in the management of retinoblastoma in man seems promising. The vista of the immunological approach in the treatment of retinoblastoma has cleared and widened by this vaccine. (Conclusion)