On the classical type of chronic familial hemolytic anemia in the Philippines

ABSTRACT

It has been claimed that the classical or Minkowski-Chauffard type of chronic familial hemolytic anemia does not exist among Filipinos. This type is presented in this paper in a father and a daughter. Both recovered completely after splenectomy. Spherocytosis, increased fragility of the red cells and the typical histological findings in the spleen as the most important differential diagnostic features, are discussed. The differential diagnosis of the Stransky-Regala-type and malaria are likewise discussed. (Summary and Conclusions)