Preliminary clinical experiences on the use of antimicrobials in cholera El Tor

ABSTRACT

A total of 184 actual and suspected cases of Cholera El Tor were admitted during a 4-month period from August to November, 1969. There were 70 pediatric and 114 adult cases. The mortality rate is 7.1% for children and 1.7% for adults. Bacteriologically positive rectal swabs were obtained in 80%. This study shows that the use of antimicrobials, either trimethoprim-sulfamethoxazole, nalidixic acid or chloramphenicol, significantly reduced the duration in days of positivity of rectal swabs.(Author)