Two Cases of Generalized Granuloma Annulare in Infants
Annals of Dermatology
;
: 122-125, 2007.
Article
in English
| WPRIM
| ID: wpr-96374
ABSTRACT
Generalized granuloma annulare (GGA) is characterized by disseminated necrotic dermal papules but the pathogenesis has not been fully elucidated. A 5-month and a 3-month male infant had diffusely scattered, erythematous papules on their trunks, and upper and lower extremities. Histopathological examination revealed an infiltration of histiocytes around and between altered collagen fibers in upper and mid dermis. The collagen fibers were separated by mucin, which was positively stained with alcian blue at pH 2.5. After they were treated with topical and/or systemic corticosteroid, the lesions disappeared. To the best of our knowledge, these two cases are non-perforating GGA in the youngest patients yet reported in English literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Collagen
/
Granuloma Annulare
/
Dermis
/
Lower Extremity
/
Alcian Blue
/
Granuloma
/
Histiocytes
/
Hydrogen-Ion Concentration
/
Mucins
Limits:
Humans
/
Infant
/
Male
Language:
English
Journal:
Annals of Dermatology
Year:
2007
Type:
Article
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