Comparative study of fleroxacin vs. chloramphenicol in typhoid fever at San Lazaro Hospital

ABSTRACT

Typhoid fever remains endemic in the Philippines. Chloramphenicol remains the drug of choice but concerns on cost effectiveness have paved way to investigations on equally efficacious agents. The fluoroquinolones, specifically fleroxacin, shows promise in the treatment of typhoid fever In this clinical trial that compared efficacy and safety of chloramphenicol and fleroxacin in typhoid fever, fleroxacin was shown to be equally efficacious and safe. (Author)