A clinical study of systemic lupus erythematosus in children / 소아과
Korean Journal of Pediatrics
;
: 74-78, 2007.
Article
in Korean
| WPRIM
| ID: wpr-9647
ABSTRACT
PURPOSE:
Systemic lupus erythematosus (SLE) is a chronic multisystemic autoimmune disease with complex clinical manifestations. It probably involves genetic, environmental and immunologic factors. In this study, we investigated the clinical manifestations, laboratory findings and prognosis of pediatric SLE to aid clinical care of pediatric SLE.METHODS:
The data of 45 patients who were diagnosed as pediatric SLE in Severance Children's Hospital from Jan. 1996 to Dec. 2005 were analysed retrospectively.RESULTS:
The mean age at diagnosis was 10.8 (0-15) years old. And the ratio of male to female patients was 14. The initial manifestations were facial edema (51.1 percent), malar rash (44.4 percent), and fever (28.9 percent). The ANA (97.8 percent), anti-ds DNA antibody (82.2 percent), lupus nephritis (71.1 percent), malar rash (71.1 percent), and cytopenia (66.7 percent) were the most common findings among the classification criteria by ACR (American College of Rhematology, 1997).CONCLUSION:
Clinical manifestations and prognosis are various in pediatric SLE. Intensive studies of SLE in children should be continued for more effective treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Autoimmune Diseases
/
Lupus Nephritis
/
DNA
/
Retrospective Studies
/
Classification
/
Diagnosis
/
Edema
/
Exanthema
/
Fever
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Pediatrics
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS