Two pediatric cases with hematuria, normal renal function and positive antineutrophil cytoplasmic antibodies
Childhood Kidney Diseases
;
: 86-90, 2022.
Article
in English
| WPRIM
| ID: wpr-966513
ABSTRACT
Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis requires prompt diagnosis and treatment, since renal function at the time of diagnosis is significantly associated with renal outcomes. Here, we report two pediatric patients with ANCA-positive glomerulonephritis initially presenting with hematuria, mild proteinuria, and normal renal function. The first patient with a high myeloperoxidase-ANCA titer (>134 IU/mL) was diagnosed with rapidly progressive glomerulonephritis based on renal biopsy and treated with immunosuppressive therapy after 10 months of follow-up. The second patient with a low myeloperoxidase-ANCA titer (11 IU/mL) maintained normal kidney function without medication. Two cases showed different clinical course according to ANCA titer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Childhood Kidney Diseases
Year:
2022
Type:
Article
Similar
MEDLINE
...
LILACS
LIS