A Case of Dermatofibroma with Granular Cells / 대한피부과학회지
Korean Journal of Dermatology
;
: 761-764, 1999.
Article
in Korean
| WPRIM
| ID: wpr-96663
ABSTRACT
Dermatofibroma with granular cells is composed mainly of spindle shaped cells mixed with in-conspicuous foamy cells that contain granular cytoplasm. We present a case of dermatofibroma with granular cells in a 36-year-old male who visited our clinic to evaluate a slow-growing nodule on the medial side of the left lawer leg. He have had the nodule for five years and sometimes felt an itching sensation. Biopsy of the nodule identified a dermal nodular tumor showing cellular spindle cell proliferation admixed with peripheral foamy histiocytes. With the immunohistochemical staining, the granular cell was positive for alpha-1-antitrypsin and CD68, and negative for S-100. A few electron-dense granules were seen in the cytoplasm on the electronmicroscopic study. These results suggested that the granular cells originated from histiocytes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pruritus
/
Sensation
/
Biopsy
/
Histiocytoma, Benign Fibrous
/
Cytoplasm
/
Cell Proliferation
/
Histiocytes
/
Leg
Limits:
Adult
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1999
Type:
Article
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