The anti-thrombotic activity of surfactins
Journal of Veterinary Science
; : 353-355, 2005.
Article
in En
| WPRIM
| ID: wpr-96781
Responsible library:
WPRO
ABSTRACT
Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner. Our findings suggest that surfactins are able to prevent a platelet aggregation leading to an inhibition of additional fibrin clot formation, and to enhance fibrinolysis with facilitated diffusion of fibrinolytic agents.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Peptides, Cyclic
/
Bacillus subtilis
/
Blood Platelets
/
Platelet Aggregation Inhibitors
/
Fibrinolytic Agents
Limits:
Humans
Language:
En
Journal:
Journal of Veterinary Science
Year:
2005
Type:
Article