A Case of Complete Regression of Hepatocellular Carcinoma during Administration of COX-2 Inhibitor / 대한간학회지
The Korean Journal of Hepatology
;
: 449-454, 2006.
Article
in Korean
| WPRIM
| ID: wpr-96787
ABSTRACT
Overexpression of cyclooxygenase-2 (COX-2) has been associated with hepatocarcinogenesis. Inhibitors of COX-2 have proapoptotic and antiproliferative effects on malignant tumors and inhibit tumor invasion to the surrounding tissues. We report here a case of complete regression of advanced hepatocellular carcinoma (HCC) during COX-2 inhibitor administration. An eighty-year-old female was diagnosed as an advanced HCC, which was associated with HCV infection. She received COX-2 inhibitor for 3 months due to degenerative arthritis of both knees. Tumor enhancement on arterial phase CT completely disappeared without specific treatment for the HCC, and the tumor size decreased on the follow-up CT scan.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pyrazoles
/
Sulfonamides
/
Sulfones
/
Antineoplastic Combined Chemotherapy Protocols
/
Diclofenac
/
Carcinoma, Hepatocellular
/
Cyclooxygenase 2 Inhibitors
/
Lactones
/
Liver Neoplasms
Limits:
Aged
/
Aged80
/
Female
/
Humans
Language:
Korean
Journal:
The Korean Journal of Hepatology
Year:
2006
Type:
Article
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