Transformation of CD5-Negative Follicular Lymphoma into CD5-Positive Diffuse Large B-Cell Lymphoma: A Case Report / 대한내과학회지
Korean Journal of Medicine
;
: 263-267, 2012.
Article
in Korean
| WPRIM
| ID: wpr-96831
ABSTRACT
Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of aggressive lymphomas. Approximately 10% of DLBCL cases express CD5 as a surface antigen. CD5-positive DLBCL can occur as the de novo or secondary type. De novo CD5-positive DLBCL arises without previous lymphoproliferative disease, and secondary CD5-positive DLBCL may or may not manifest as Richter syndrome. The transformation of follicular lymphoma (FL) into DLBCL occurs in approximately one-third of all cases. The transformation of CD5-negative low-grade B-cell lymphoma to CD5-positive DLBCL is extremely rare. We report the clinical features of a rare case that presented with a transformation from CD5-negative FL to CD5-positive DLBL over 11 years. This is the second such case published in the English literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
B-Lymphocytes
/
Cell Transformation, Neoplastic
/
Lymphoma, B-Cell
/
Lymphoma, Follicular
/
Lymphoma, Large B-Cell, Diffuse
/
Lymphoma
/
Antigens, Surface
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2012
Type:
Article
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