Prenatal Diagnosis of Wilms Tumor / 대한소아혈액종양학회지
Korean Journal of Pediatric Hematology-Oncology
;
: 202-206, 1998.
Article
in Korean
| WPRIM
| ID: wpr-9691
ABSTRACT
Early diagnosis of childhood cancer is very important for the prognosis. Ultrasonography of routine examination for pregnant woman is now a popular method. We experienced two cases of congenital Wilms tumor suspected by prenatal ultrasonography from mothers and confirmed by nephrectomy soon after birth. One of the cases was stage II with favorable histology and was treated with vincristine(2.0 mg/m2) and actinomycin D(45 microgram/kg) for 60 weeks by National Wilms Tumor Study(NWTS) IV treatment protocol, K-4 A regimen. The other was stage I with favorable histology and was treated with vincristine(1.5 mg/m2) and actinomycin D(15 microgram/kg) for 24 weeks by NWTS IV, EE regimen. The post-chemotherapy follow-up evaluation of these two children for 3 years and 2 months and 1 year and 7 months respectively were quite normal with 100% of Karnovsky scores. Early diagnosis, especially in prenatal, is very important for the prognosis of childhood cancer. Routine ultrasonographic examination in pregnant women is also desirable for the detection of solid tumor of fetus if it does not harmful for the fetus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prenatal Diagnosis
/
Prognosis
/
Clinical Protocols
/
Follow-Up Studies
/
Ultrasonography, Prenatal
/
Ultrasonography
/
Wilms Tumor
/
Dactinomycin
/
Parturition
/
Pregnant Women
Type of study:
Diagnostic study
/
Practice guideline
/
Observational study
/
Prognostic study
/
Screening study
Limits:
Child
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Pediatric Hematology-Oncology
Year:
1998
Type:
Article
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