Two pairs of phloroglucinol enantiomers from Hypericum wightianum and their stereochemical structures / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 421-429, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-970479
ABSTRACT
The chemical constituents in the ethanol extract of Hypericum wightianum(Hypericaceae) were purified by column chromatography and identified via magnetic resonance imaging(NMR), high-resolution mass spectrum, and circular dichroism. A total of 22 compounds were identified, including eight polyprenylated phloroglucinols(1-8), three chromones(9-11), and three terpenoids(14-16) and so on. Among them, compounds 16 and 17 were first reported in the genus Hypericum, and compounds 1-11, 14, 15, and 19 were first isolated from H. wightianum. Compounds 1-4 were previously reported as two pairs of enantiomers. This study reported the chiral resolutions and absolute configurations of compounds 1-4 for the first time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phloroglucinol
/
Drugs, Chinese Herbal
/
Magnetic Resonance Spectroscopy
/
Molecular Structure
/
Hypericum
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2023
Type:
Article
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