Recent studies on dilated cardiomyopathy caused by TTN mutations in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 217-222, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-971063
ABSTRACT
The mutations of TTN gene that encodes titin are the most common mutation type among the genetic causes of dilated cardiomyopathy (DCM). This article reviews the worldwide studies on potential molecular pathogenesis (transcription, post-translational modification, etc.), clinical phenotypes, and gene therapies of pediatric DCM caused by TTN mutations, with the hope of providing a reference for the precision treatment of pediatric DCM caused by TTN mutations.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phenotype
/
Cardiomyopathy, Dilated
/
Genetic Therapy
/
Connectin
/
Mutation
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2023
Type:
Article
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