Evaluation of COVID-19 Antigen Test Kit Assay Analytical and Clinical Performance / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
;
(6): 99-105, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-971312
ABSTRACT
Objective To rapidly screen patients with novel coronavirus pneumonia (COVID-19) infection including asymptomatic ones. Method Established a rapid detection test kit, and evaluated analytical and clinical performance of it. Result The minimum limit of detection of the reagent was 9.75×102 TCID50/mL; there was no cross-reaction and interference in the high-concentration samples of 29 common respiratory pathogens tested. The diagnostic sensitivity of clinical samples was 98.56%, specificity was 99.00%, and the total coincidence rate was 98.85%; the consistency test Kappa value is 0.974 5. The stratified analysis of positive samples with different Ct values showed that the coincidence rate within each stratum was greater than 95%. Conclusion This COVID-19 antigen test kit with excellent detection performance, fast detection speed, and portable operation. It can be used as a supplementary method for existing nucleic acid detection methods for early screening of new coronavirus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sensitivity and Specificity
/
COVID-19 Testing
/
SARS-CoV-2
/
COVID-19
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Medical Instrumentation
Year:
2023
Type:
Article
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